|
What Are Diuretics?
Diuretics are medicines that
remove water from the body by increasing the amount of urine
the kidneys produce. They are often known as "water
tablets".
Types of
Diuretics? There are 3
types of diuretic medicines.
Each type works a little differently, but they
all lower the amount of salt and water in your body, which
helps to lower your blood pressure: Thiazides, loop
diuretics and potassium-sparing diuretics (eg amiloride)
How
Diuretics Works?
Thiazides, loop
diuretics and potassium-sparing diuretics all work on the
kidneys. The
kidneys have a network of tubes that make urine by filtering
the blood in two stages. In the first stage, the water, salt
and the waste products such as urea are filtered out from
the blood, leaving behind the red and white blood cells. But
lots of nutrients and other essential substances also leave
the blood at this stage.
In the second stage there is a backwards filter, where the
kidneys re-absorb the nutrients and essential substances
back into the blood. This leaves the waste products, plus
some salt and water, in the kidneys. This waste leaves the
kidneys as urine.
Heart failure makes the kidneys re-absorb more water and
salt into the blood, and so produce less urine. This is the
body's way of trying to compensate for the reduced pumping
power of the heart, but it actually makes matters worse.
There is a bigger volume of blood for the heart to pump, and
so more work for it to do. Also the excess water in the
blood tends to leak out into the lungs, which can lead to
breathlessness. Heart failure can also make your ankles and
feet swell up.
Diuretics reduce the amount of water and salt that is
re-absorbed by your kidneys. So, more water and salt passes
out with the waste products into your urine. This means that
you make more urine. As a result of this loss of water from
the blood, the overall volume of blood is reduced. This
gives your heart less work to do and helps to reduce the
pressure of blood in your arteries, which is what high blood
pressure actually is.
|